Cannabinoids THC [Tetrahydrocannabinol] and CBD [Cannabidiol] are the two cannabis compounds that are grabbing the attention of the medical community. How THC and CBD interact with human endocannabinoid receptors when they enter the body is fascinating. The human body has multiple cannabinoid receptors across the body responsible for specific physiological effects. The cannabinoids have the potential to treat –

  • Nausea
  • Pain
  • Cancer
  • Muscle spasms
  • Alzheimer’s
  • Cancer
  • Multiple sclerosis
  • Glaucoma

The notable difference between THC and CBD compound is the latter lacks in causing psychoactive effects that are associated with marijuana characteristic. It is THC that gives the mind-altering high. If you want to use weed for health benefit without the high, then choose CBD vape pen. On, you will come across refillable and disposable vape pens. 


Both interact with your endocannabinoid system [ECS], but besides the differences in causing high, there is some major difference you need to know.


THC and CBD are there in the cannabis plant. Nevertheless, the different strain has a diverse proportion of THC and CBD. In general, for medical marijuana purposes, CBD extracted from hemp is regarded to be legal. The industrial hemp plant is cultivated with less than 0.3% of THC and is CBD dominant. Hemp belongs to the cannabis family. THC extract is got from the marijuana plant. 


The medical benefits are the same for both, but people use CBD to treat –

  • IBD
  • Seizures
  • Inflammation
  • Depression
  • Migraines
  • Mental disorders

THC has the potential to treat –

  • Muscle spasm
  • Glaucoma
  • Insomnia
  • Lack of appetite

Both can be used to treat anxiety, pain, and nausea.


On the state level, the use of marijuana for recreational or medicinal purpose differs. At the federal level, using marijuana is still illegal. Laws associated with the use of marijuana change, so check the local laws regularly.

Side effects

The World Health Organization has found CBD to be safe, and the possible side effects can be because of its interaction with other prescribed medication the user may be taking. The side effects associated with THC are temporary. It includes –

  • Red eyes
  • Dry mouth
  • Slow response time
  • Memory loss
  • Euphoric feel
  • Increase in heart rate
  • Coordination problem

According to studies, neither THC nor CBD has serious or fatal side effects, if taken correctly. 

Methods to take

CBD is available in different forms like supplements, gels, oils, and gummies. THC is also available in a variety of forms including oils, tinctures, smokable products, capsules, and edibles. 

When CBD and THC are taken together?

CBD and THC are both helpful in treating a medical condition. You can even take both together for an entourage effect. However, the ratio to take will depend on the medical condition and the goal. 

For example, a person using cannabis-based medicine for pain relief will have a different ratio than the Cohn’s disease patient using it to get relief from nausea. If you desire to take both, discuss this with your doctor. There is no standard dosage that works for all. 


When you try THC or/ and CBD start with a low dosage, and if necessary, increase slowly. Experiment with different delivery methods and find out, which works best for your condition.